European Mast Cell and
Basophil Research Network

Author: Webservice

Mast Cell Cytonemes as a Defense Mechanism against Coxiella burnetii

Summary Mast cells (MCs) are critical mediators of inflammation; however, their microbicidal activity against invading pathogens remains largely unknown. Here, we describe a nonpreviously reported antibacterial mechanism used by MCs against Coxiella burnetii, the agent of Q fever. We show that C. burnetii interaction with

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Progenitor mast cells and tryptase in Q fever

Summary Q fever is an infectious disease due to Coxiella burnetii. Following a primary-infection, C. burnetii may persist in some patients, leading to endocarditis and vascular infections. Mast cells (MCs), known for their role in allergic diseases, innate immunity and cardiac function, are produced by

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