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Entries:
Mast cells and pain
Mast cells are emerging players in physiological and pathological pain pathways. Mast cells are frequently found in close proximity to nociceptive neurons and therefore can
Mast cells in asthma
Asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness, airway inflammation, and airway remodeling. Mast cells (MC) activated through IgE, and specific allergens, release
Mast cells in innate and adaptive immunity
Mast cells (MCs) are now regarded not only as effector cells playing a detrimental role in IgE-mediated allergic responses (Fig. 1) but also and more
Mast cells proteases
Introduction The most striking morphological feature of mast cells is their numerous cytoplasmic secretory granules. These are filled with preformed compounds (“mediators”), which are rapidly
Mast cells, hormones and pregnancy
In mammals, the successful implantation of the blastocyst into the endometrium and the subsequent development of a decidual cell response involve many interactions between the
Microtubules and mast cell signaling
Activation of mast cells is characterized by dramatic changes in cell morphology, intracellular transport and exocytosis. All these processes depend on the activities of cytoskeletal
