European Mast Cell and
Basophil Research Network


Dear Mast Cell and Basophil Fans!

You have entered the MastoBasoWiki – a platform to share and exchange knowledge about mast cells and basophils as well as related topics. The platform aims to serve as an informative tool for researchers, students and everyone interested in learning more about our favorite cells.

If you are also a mast cell and basophil fan and you want to share your knowledge with the community please feel free to contact us and send us your ideas how to improve and complement the MastoBasoWiki.

Enjoy the entries.


Mast cells and pain

Mast cells are emerging players in physiological and pathological pain pathways. Mast cells are frequently found in close proximity to nociceptive neurons and therefore can

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Mast cells in asthma

Asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness, airway inflammation, and airway remodeling. Mast cells (MC) activated through IgE, and specific allergens, release

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Mast cells proteases

Introduction The most striking morphological feature of mast cells is their numerous cytoplasmic secretory granules. These are filled with preformed compounds (“mediators”), which are rapidly

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Mast cells, hormones and pregnancy

In mammals, the successful implantation of the blastocyst into the endometrium and the subsequent development of a decidual cell response involve many interactions between the

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Microtubules and mast cell signaling

Activation of mast cells is characterized by dramatic changes in cell morphology, intracellular transport and exocytosis. All these processes depend on the activities of cytoskeletal

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