Mast cells (MC) accumulate in colorectal cancer (CRC) and the relationship between MC density and cancer progression has been well recognized.
Yu Y, Blokhuis BRJ, Diks MAP, Keshavarzian A, Garssen J and Redegeld FA (2018) Functional Inhibitory Siglec-6 Is Upregulated in Human Colorectal Cancer-Associated Mast Cells. Front. Immunol. 9:2138. doi: 10.3389/fimmu.2018.02138
Summary Chronic urticaria (CU) is a mast cell (MC)-dependent disease with limited therapeutic options. Current management strategies are directed at inhibiting IgE-mediated activation of MCs and
Summary Staphylococcus aureus (SA) and its exotoxins activate eosinophils (Eos) and mast cells (MCs) via CD48, a GPI-anchored receptor belonging to the Signaling Lymphocytes Activation Molecules (SLAM)
K. Frank Austen, a remarkable, dedicated mast cell scientist and mentor over almost seven decades, passed away on June 23rd at an age of 95 years.