European Mast Cell and
Basophil Research Network

Vadym Sulimenko

Microtubules and mast cell signaling

Activation of mast cells is characterized by dramatic changes in cell morphology, intracellular transport and exocytosis. All these processes depend on the activities of cytoskeletal filamentous structures – microtubules, microfilaments and intermediate filaments. Different regulatory pathways regulate cytoskeletal functions indispensable for mast cell degranulation. Microtubules

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