European Mast Cell and
Basophil Research Network

Author: Ivana Hálová

Transmembrane adaptor proteins in mast cells

Transmembrane adaptor proteins (TRAPs) facilitate activation within signal transduction pathways but lack both intrinsic enzymatic and transcriptional activities. They are characterized by a short extracellular domain, a single transmembrane domain and a cytoplasmic tail with various motifs serving as anchors for cytoplasmic signaling molecules. TRAPs

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