European Mast Cell and
Basophil Research Network

Author: Sheli Friedman

Mast cells activating receptors

General description Mast cells (MC) are best known for their crucial role in the allergic response, but their strategic location and richness of pre-stored and newly synthesized mediators have clearly demonstrated their significance also in innate and adaptive immune responses, inflammation, and tissue remodeling. MC

Read More »

Mast cell inhibitory receptors

Mast cells receptors – general description Mast cells (MC) are key effector cells in allergic inflammation (AI) but are also involved in regulating fibrosis, in tissue responses to neoplastic diseases, in autoimmune diseases and in host‑defense against bacterial and parasitic infections [1]. In allergy, the

Read More »