European Mast Cell and
Basophil Research Network

Anja Rabenhorst

The role of mast cells in the microenvironment of tumors

Hallmarks of cancer The hallmarks of cancer include, according to Hanahan and Weinberg1, ten different mechanisms, as shown in Figure 1. Inflammation plays an important role in different stages of tumor development, including initiation, promotion, malignant conversion, invasion and metastasis.2 Here, tumor-infiltrating immune cells interact

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