European Mast Cell and
Basophil Research Network

Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models

Summary

Chronic inflammation drives the development of colorectal cancer (CRC), where tumor-infiltrating immune cells interact with cancer cells in a dynamic crosstalk.

Citation

Yingxin Yu, Bart Blokhuis, Yvonne Derks, Sangeeta Kumari, Johan Garssen & Frank Redegeld (2018) Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models, OncoImmunology, 7:11, e1504729, DOI: 10.1080/2162402X.2018.1504729

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    Recording: 1st EMBRN webinar 2025

    1st EMBRN webinar took place on October 8, 2025. This event highlights exciting new research on mast cells and skin immunity. Thomas Plum was our keynote speaker

    October 10, 2025