European Mast Cell and
Basophil Research Network

Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models

Summary

Chronic inflammation drives the development of colorectal cancer (CRC), where tumor-infiltrating immune cells interact with cancer cells in a dynamic crosstalk.

Citation

Yingxin Yu, Bart Blokhuis, Yvonne Derks, Sangeeta Kumari, Johan Garssen & Frank Redegeld (2018) Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models, OncoImmunology, 7:11, e1504729, DOI: 10.1080/2162402X.2018.1504729

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