European Mast Cell and
Basophil Research Network

Author: Martin Köberle

Role of tetraspanins in mast cells

Tetraspanins are modulators of mast cell degranulation Mast cell (MC) degranulation basically is the result of FceRI cross-linking by IgE bound antigen. However, this process is mediated by a complex signaling machinery, sometimes referred to as the FceRI signalosome (1). Tetraspanin proteins have been named

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