European Mast Cell and
Basophil Research Network

Author: Salah Mecheri

Mast cells in innate and adaptive immunity

Mast cells (MCs) are now regarded not only as effector cells playing a detrimental role in IgE-mediated allergic responses (Fig. 1) but also and more importantly as key players in host defences including via allergy-mediated processes. In this respect, mast cell responses during hypersensitivity reactions

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