European Mast Cell and
Basophil Research Network

Author: Paulo De Sepulveda

KIT Receptor (CD117, SCF receptor, Mast Cell Growth Factor)

General Description and Physiological Function KIT is a transmembrane receptor, member of the receptor tyrosine kinase family and structurally related to the PDGF, CSF-1 (M-CSF) and FLT3 receptors. It is encoded by the c-kit gene, the cellular homolog of v-kit Hardy-Zuckerman 4 feline sarcoma viral

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