European Mast Cell and
Basophil Research Network

Author: Rosa Torres

Mast cells in asthma

Asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness, airway inflammation, and airway remodeling. Mast cells (MC) activated through IgE, and specific allergens, release mediators that drive early phase reactions (EPR), contribute to late phase reaction (LPR), and also take part in airway remodeling.

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